ANTIANGINAL DRUGS PPT FREE DOWNLOAD

On the other side, the nitro group and the ester moieties are nonessentials. Toxicities Constipation, pretibial edema, nausea flushing and dizziness Heart failure, AV blockade and sinus node depression Verapamil By Gaurav Kayal. Efficiency of O 2 utilization By Gaurav Kayal. Pharm Assistant Professor Pharmaceutical Chemistry. Action on platelets Decrease platelet aggregation 4. Venodilation decreased diastolic heart size and fiber tension Arteriolar dilation reduced peripheral resistance and BP Overall reduction in myocardial fiber tension, O 2 consumption and double product No direct effects on the cardiac muscle Can cause reflex tachycardia and increased force of contraction when reducing BP By Gaurav Kayal.

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Converting the aromatic portion to phenanthrene or anthracene decrease the activity. Nitrates Calcum channel blockers Beta blocking agents Adverse effects and contrdictions.

Chemistry And SAR of Antianginal-Drugs |authorSTREAM

Postural hypotension Due to reduction of central venous pressure. Propranolol Atenolol Metoprolol Calcium channel blockers: Alpha methyl group at side chain decrease activity. We think you have liked this presentation. Introduction Branching off the aorta antiangiinal the coronary arteries.

Cardiovascular pharmacology Chapter 32 Antianginal drugs China Medical University.

Methaemoglobinaemia Due to formation of methaemoglobin from haemoglobin. Mibefradil By Gaurav Antianginal drugs ppt. In Verapamil pppt related drugs the essentials features are: Auth with social network: WordPress Embed Customize Embed.

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In order to view it, please contact the author of the xntianginal. Venodilation decreased diastolic heart size and fiber tension Arteriolar dilation reduced peripheral resistance and BP Overall reduction in myocardial fiber tension, O 2 consumption and double product No direct effects on the cardiac muscle Can cause reflex tachycardia and increased force of contraction when reducing BP By Gaurav Kayal PowerPoint Presentation: Rapidly developed tolerance due to rapid administration of drug within a short interval of time antianginal drugs ppt called tachyphylaxis.

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Upload from Desktop Single File Upload. Upload from Desktop Single File Upload. Aspirin reduces platelet aggregation Classifications of drubs medicine. Calcium Antianginal drugs ppt Blockers Nifedipine, Dihydropyridine, Diltiazem, Verapamil Differ markedly in structure but all are orally active with half-lives of hours Nimodipine Member of the dihydropyridine family Approved only for the treatment of stroke associated with subarachnoid hemorrhage Bepridil Similar structure to verapamil, Longer duration of action, Greater cardiovascular toxicity By Gaurav Kayal.

On the other side, the nitro group and the ester moieties are nonessentials. Antiamginal of O 2 utilization By Gaurav Kayal. It occurs when there is a deficit antianginal drugs ppt myocardial oxygen supply in relation to myocardial oxygen demand. Automatically changes to Flash or non-Flash embed.

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Mechanism of action of Nitroglycerine: SAR of Calcium Channel Blockers In phenyldihydropyridine derivatives the structural features essential for activity are: Organ System Effects 1. Action on platelets Decrease platelet aggregation 4. You do not have the permission to view this presentation. Verapamil hydrochloride By Gaurav Kayal.

Types of Angina contd.

ANGINA PECTORIS & ANTIANGINAL DRUGS |authorSTREAM

Angina pain is characterized by sudden severe pressing substernal pain radiating to the left arm. The O-CH 2 group between aromatic ring and the ethylamino side chain is responsible for the antagonistic property.

The carbon side chain having hydroxyl group must be S- configuration for optimum ddrugs to beta receptor. Flashing of face Due to dilatation of blood vessels in facial region.

Published by Bathsheba Webb Modified over 3 years ago. Adverse effects of organic nitrates 1.